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What is the Survivin Vaccine?
Anti-Survivin Vaccine is a type of immunotherapy called a cancer vaccine, which acts to educate the immune system to identify and target cells producing proteins that are associated with cancer.
The immune system recognizes antigens, substances associated with a disease that are not normally produced by the body. Specific immune cells called antigen presenting cells (APCs) identify and process these antigens. They then activate another type of immune cell called T-cells to recognize and kill the cells producing the antigen.
Around 95 percent of neuroendocrine tumors and other solid tumors produce a protein called survivin, which is rarely present in the body. Anti-survivin vaccine consists of a peptide, part of the survivin protein, that can be recognized as an antigen by the immune system. The peptide is attached to a metalloprotein called keyhole limpet hemocyanin (KLH), which can boost the immune response against the peptide.
When Anti-survivin vaccine is injected into the patient, the immune system stimulates the production of T-cells that target the survivin-producing tumor cells, reducing the tumor size or preventing tumor growth.
Anti-survivin vaccine is administered in combination with the adjuvant or “helper drug” Leukine (sargramostim or GM-CSF), which acts to boost the numbers and activity of immune cells such as APCs.
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Request information without obligation, we will study your case with our medical team to give you an answer as soon as possible.
Request information without obligation
Request information without obligation, we will study your case with our medical team to give you an answer as soon as possible.
